Genmab Reallocates Resources, Halts Acasunlimab Program To Accelerate Priority Pipeline Assets

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Genmab A/S (GMAB) announced Monday that it will suspend further clinical development efforts for acasunlimab, redirecting resources toward high-priority programs with greater commercial and clinical potential. The decision aligns with the company’s strategic capital allocation framework and portfolio optimization strategy.

The biotech firm is concentrating its investments on late-stage assets including EPKINLY, petosemtamab, and rinatabart sesutecan—programs management believes offer more compelling benefits for both patients and shareholders. CEO Jan van de Winkel stated: “While acasunlimab demonstrated encouraging results, our priority remains maximizing impact where we see the strongest opportunity for success. This reallocation reflects our commitment to deploying capital where it matters most.”

The strategic shift carries significant implications for the company’s near-term priorities. Notably, Genmab has confirmed that this program discontinuation will not adversely affect the company’s full-year 2025 financial outlook, suggesting the reallocated resources will support ongoing priority initiatives without requiring revised guidance.

Market reaction was modest, with Genmab shares trading at $32.72 in pre-market activity on the Nasdaq, representing a 2.09 percent decline. The move underscores how biotech companies continuously reassess their portfolios to align resources with their highest-impact priorities and long-term strategic objectives.

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